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GP of Mexico Mexico City 18-10-1987m 68 laps of 4.421 m, Total distance
300.628 m
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| Pos | No | Driver | Team-engine | Diff | Reason |
| 1 | 5 | Nigel Mansell | Williams-Honda FW11B | 1:26:24.207 | - |
| 2 | - | Nelson Piquet | Williams-Honda FW11B | -26.176 | - |
| 3 | 7 | Riccardo Patrese | Brabham-BMW BT56 | -1:26.879 | - |
| 4 | - | Eddie Cheever | Arrows-Megatron A10 | -1:41.352 | - |
| 5 | - | Teo Fabi | Benetton-Ford B187 | -2 laps | - |
| 6 | - | Philippe Alliot | Lola-Ford LC87 | -3 laps | - |
| 7 | - | Jonathan Palmer | Tyrrell-Ford DG016 | -3 laps | - |
| 8 | - | Philippe Streiff | Tyrrell-Ford DG016 | -3 laps | - |
| 9 | - | Yannick Dalmas | Lola-Ford LC87 | -4 laps | - |
| 10 | 12 | Ayrton Senna | Lotus-Honda 99T | -9 laps | Spun |
| 11 | - | Ivan Capelli | March-Ford 871 | -12 laps | Engine |
| 12 | - | Alex Caffi | Osella-Alfa Romeo FA1L | -13 laps | Engine |
| 13 | - | Piercarlo Ghinzani | Ligier-Megatron JS29C | -20 laps | Water leak |
| 14 | - | Adrian Campos | Minardi-Motori Moderni M187 | -31 lap | Transmission |
| 15 | - | René Arnoux | Ligier-Megatron JS29C | -34 laps | Overheating |
| 16 | - | Derek Warwick | Arrows-Megatron A10 | -37 laps | Collision |
| 17 | - | Andrea de Cesaris | Brabham-BMW BT56 | -41 lap | Collision |
| 18 | - | Gerhard Berger | Ferrari F187 | -43 laps | Turbo |
| 19 | - | Thierry Boutsen | Benetton-Ford B187 | -48 laps | Electrics |
| 20 | - | Alessandro Nannini | Minardi-Motori Moderni M187 | -50 laps | Turbo |
| 21 | - | Michele Alboreto | Ferrari F187 | -51 lap | Engine |
| 22 | - | Martin Brundle | Zakspeed 871 | -60 laps | Turbo |
| 23 | - | Satoru Nakajima | Lotus-Honda 99T | -62 laps | Collision |
| 24 | - | Christian Danner | Zakspeed 871 | -62 laps | Collision |
| 25 | - | Stefan Johansson | McLaren-TAG MP4/3 | -62 laps | Collision |
| 26 | 1 | Alain Prost | McLaren-TAG MP4/3 | -63 laps | Collision |
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